SCHEMBL12636737

SCHEMBL12636737

Cc1c(/N=N/c2c(C(C)(C)C)nn(C)c2N)c(-c2ccccc2)nn1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
MAPT P10636 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.35
HPGD P15428 3/20 0.35
CCNT1 O60563 1/20 0.35
CDK1 P06493 1/20 0.35
CDK4 P11802 1/20 0.35
CCNB1 P14635 1/20 0.35
CCND1 P24385 1/20 0.35
CCNE1 P24864 1/20 0.35
CDK2 P24941 1/20 0.35
CDK9 P50750 1/20 0.35
CDK8 P49336 2/20 0.34
CSF1R P07333 1/20 0.34
FGFR1 P11362 1/20 0.34
FLT1 P17948 1/20 0.34
KDR P35968 1/20 0.34
CSNK1A1 P48729 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12636742 0.82 MAPT (0.51) POLBCA1CA2MAPTSMN1; SMN2
SCHEMBL12636744 0.73 CCNT1 (0.36) POLBCCNT1CDK1CDK4CCNB1
SCHEMBL5201246 0.72 MAPT (0.47) POLBCA1CA2MAPTSMN1; SMN2
SCHEMBL15716071 0.70 CA1 (0.46) POLBCA1CA2MAPTSMN1; SMN2
SCHEMBL12636769 0.69 CA1 (0.43) POLBCA1CA2MAPTSMN1; SMN2
SCHEMBL13860397 0.68 CDK8 (0.50) POLBMAPTSMN1; SMN2HPGDCDK8
SCHEMBL4214390 0.68 MAPT (0.58) POLBMAPTSMN1; SMN2HPGDCDK8
SCHEMBL12636694 0.68 TDP1 (0.45) POLBCA1CA2MAPTRAB9A
SCHEMBL12636741 0.67 RAB9A (0.49) POLBMAPTSMN1; SMN2HPGDNPC1
SCHEMBL33804 0.66 MAPT (0.55) POLBMAPTSMN1; SMN2HPGDCDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed