Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL5550075 | 0.93 | TSHR (0.40) | TSHRNPC1RAB9AMEN1KMT2A | |
| Tetrabuthylammonium SCHEMBL5550079 | 0.93 | TSHR (0.40) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1263347 | 0.92 | NPC1 (0.41) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1263348 | 0.92 | NPC1 (0.41) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1263700 | 0.80 | MAPT (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1263701 | 0.80 | MAPT (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL12898254 | 0.74 | NPC1 (0.40) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL18785100 | 0.73 | ALDH1A1 (0.47) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1679319 | 0.73 | ALDH1A1 (0.47) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15849845 | 0.73 | ALDH1A1 (0.47) | TSHRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435696-B2 | Redox-active polymers and their applications | BROWN UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110031440-A1 | REDOX-ACTIVE POLYMERS AND THEIR APPLICATIONS | BROWN UNIVERSITY | 2011-02-10 | — | — | US | disclosed |
| US-7838687-B2 | Redox-active polymers and their applications | BROWN UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070048608-A1 | Redox-active polymers and their applications | BROWN UNIVERSITY | 2007-03-01 | — | — | US | disclosed |