Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263701 | 1.00 | MAPT (0.46) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1263348 | 0.87 | NPC1 (0.41) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1263347 | 0.87 | NPC1 (0.41) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| Tetrabuthylammonium SCHEMBL5550079 | 0.80 | TSHR (0.40) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| Tetrabuthylammonium SCHEMBL5550075 | 0.80 | TSHR (0.40) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| Tetrabuthylammonium SCHEMBL1263694 | 0.80 | TSHR (0.41) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL14922870 | 0.77 | L3MBTL1 (0.72) | MAPTSMN1; SMN2RAB9AKDM4EUSP2 | |
| SCHEMBL14922869 | 0.76 | L3MBTL1 (0.50) | SMN1; SMN2ALDH1A1CYP1A2KDM4EUSP2 | |
| SCHEMBL12926218 | 0.76 | MAPK1 (0.35) | MAPTNPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1262943 | 0.76 | MAPT (0.68) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435696-B2 | Redox-active polymers and their applications | BROWN UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110031440-A1 | REDOX-ACTIVE POLYMERS AND THEIR APPLICATIONS | BROWN UNIVERSITY | 2011-02-10 | — | — | US | disclosed |
| US-7838687-B2 | Redox-active polymers and their applications | BROWN UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070048608-A1 | Redox-active polymers and their applications | BROWN UNIVERSITY | 2007-03-01 | — | — | US | disclosed |