Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304568 | 0.81 | KDM4E (0.46) | CYP2C9ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL30149854 | 0.78 | HSD17B10 (0.46) | CYP2C9ALDH1A1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL15133691 | 0.78 | CYP2C9 (0.39) | CYP2C9ALDH1A1HPGDKDM4EHTT | |
| Hydrochloric Acid SCHEMBL16295798 | 0.77 | HSD17B10 (0.45) | CYP2C9ALDH1A1KDM4ECYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL32679705 | 0.77 | HSD17B10 (0.45) | CYP2C9ALDH1A1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL16296751 | 0.71 | CYP3A4 (0.33) | CYP3A4RECQLTSHRLMNA | |
| Hydrochloric Acid SCHEMBL12492236 | 0.71 | CYP2C9 (0.33) | CYP2C9ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL25266487 | 0.67 | MYC (0.34) | CYP2C9ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL13073788 | 0.67 | NPC1 (0.53) | CYP2C9ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL25207239 | 0.66 | MYC (0.35) | CYP2C9ALDH1A1HPGDKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879574-B2 | Folded peptide backbone each end of which is conjugated to a fluorophore, which when cleaved as by digestion with a protease, the fluorophores provide high intensity signals; histology | ONCOIMMUNIN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20090325168-A1 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-7541143-B2 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOIMMUNIN, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080199898-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-7312302-B2 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCOLMMUNIN, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1214445-A4 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-6936687-B1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCO IMMUNIN, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| US-20050158766-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOLMMUNIN, INC. | 2005-07-21 | — | — | US | disclosed |
| US-6893868-B2 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCO IMMUNIN, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20040096926-A1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCOIMMUNIN, INC. | 2004-05-20 | — | — | US | disclosed |
| US-20030207264-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOLMMUNIN, INC. | 2003-11-06 | — | — | US | disclosed |
| EP-1356084-A2 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-0988394-A4 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002061038-A9 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN INC (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002061038-A2 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| EP-1214445-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018238-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| EP-0988394-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998037226-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096926-A1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | PRSS3, PREP, CTRL | CYP2C9 2744/4885ALDH1A1 2075/4885HPGD 1436/4885 |
| US-20030207264-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | DNTT, HMBS, WRN | CYP2C9 1452/4885ALDH1A1 2193/4885HPGD 272/4885 |
| US-20050158766-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | DNTT, WRN, HMBS | CYP2C9 1205/4885ALDH1A1 2249/4885HPGD 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.