SCHEMBL126390

SCHEMBL126390

O=C(O)CC(O)(CC(=O)C(=O)O)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.75
HMGCR P04035 1/20 0.40
CHRM1 P11229 1/20 0.40
TBXA2R P21731 1/20 0.40
ADRA1A P35348 1/20 0.40
TSHR P16473 2/20 0.39
CYP2D6 P10635 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
ACLY P53396 3/20 0.38
SLC13A5 Q86YT5 4/20 0.38
CPT2 P23786 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
OR51E2 Q9H255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL8853369 0.87 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL1641736 0.87 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL725546 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL3417188 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL28641702 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL842 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL1332229 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL240402 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL1331942 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL10896997 0.87 ALDH1A1 (1.00) ALDH1A1HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136601-B2 Conversion of S-lignin compounds to useful intermediates ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2021-10-05 US claimed
US-20200071731-A1 CONVERSION OF S-LIGNIN COMPOUNDS TO USEFUL INTERMEDIATES Alliance for Energy Innovation, LLC 2020-03-05 US claimed
WO-2017165689-A2 CONVERSION OF BIOMASS TO USEFUL INTERMEDIATES ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2017-09-28 WO claimed
US-20170275655-A1 CONVERSION OF BIOMASS TO USEFUL INTERMEDIATES Alliance for Energy Innovation, LLC 2017-09-28 US claimed
WO-2025230736-A1 ENGINEERED BIOCATALYSTS FOR THE SYNTHESIS OF GAMMA-HYDROXY AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-11-06 WO disclosed
US-12104160-B2 Production of 4,6-dihydroxy-2-oxo-hexanoic acid ZYMOCHEM, INC. (US) 2024-10-01 US disclosed
US-20240191053-A1 SYSTEMS, MICROORGANISMS, OR METHODS FOR WASTE PET VALORIZATION WASHINGTON UNIVERSITY (US) 2024-06-13 US disclosed
US-11845972-B2 Muconic acid-producing transformed microorganism and use thereof HIROSAKI UNIVERSITY (JP) 2023-12-19 US disclosed
US-11807873-B2 Conversion of S-lignin compounds to useful intermediates ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2023-11-07 US disclosed
US-20220389433-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES ZYMOCHEM, INC. 2022-12-08 US disclosed
US-11518975-B2 Engineered microorganisms for the production of intermediates and final products ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2022-12-06 US disclosed
WO-2022221338-A2 SYSTEMS, MICROORGANISMS, OR METHODS FOR WASTE PET VALORIZATION WASHINGTON UNIVERSITY (US) 2022-10-20 WO disclosed
WO-2007133183-A2 POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF STEREOISOMERS OF MONATIN AND THEIR PRECURSORS CARGILL, INCORPORATED (US) 2007-11-22 WO disclosed
WO-2007103389-A9 ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM CARGILL INC (US) 2007-11-01 WO disclosed
WO-2007103389-A2 ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM CARGILL, INCORPORATED (US) 2007-09-13 WO disclosed
WO-2007103989-A2 ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM VERENIUM CORPORATION (US) 2007-09-13 WO disclosed
US-20060252135-A1 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors CARGILL, INCORPORATED (US) 2006-11-09 US disclosed
EP-1678313-A2 PRODUCTION OF MONATIN AND MONATIN PRECURSORS CARGILL, INCORPORATED (US) 2006-07-12 EP disclosed
US-20050221455-A1 Production of monatin and monatin precursors CARGILL, INC. 2005-10-06 US disclosed
WO-2005042756-A2 PRODUCTION OF MONATIN AND MONATIN PRECURSORS CARGILL, INCORPORATED (US) 2005-05-12 WO disclosed