SCHEMBL126400

SCHEMBL126400

C#CCOc1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA4 P22748 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
MAOB P27338 11/20 0.58
MAOA P21397 7/20 0.58
ACHE P22303 1/20 0.58
GSTP1 P09211 1/20 0.53
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 2/20 0.52
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19742209 0.98 CA12 (0.56) CA12CA1CA2CA4CA7
SCHEMBL20530610 0.94 MAOB (0.62) CA12CA1CA2CA4CA7
SCHEMBL5704167 0.88 CA12 (0.63) CA12CA1CA2CA4CA7
Hydrochloric Acid SCHEMBL21694040 0.85 CA12 (0.61) CA12CA1CA2CA4CA7
SCHEMBL20530611 0.82 MAOB (0.54) CA12CA1CA2CA4CA7
SCHEMBL15800551 0.81 CA12 (0.57) CA12CA1CA2CA4CA7
SCHEMBL9155218 0.81 GSTP1 (0.68) CA12CA1CA2CA4CA7
SCHEMBL14645171 0.81 APP (0.57) CA12CA1CA2CA4CA7
SCHEMBL31691312 0.80 ALDH1A1 (0.65) CA12CA1CA2CA4CA7
SCHEMBL18844813 0.79 TAAR1 (0.52) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707842-A Proteome targeting labeling capture probe and preparation method and application thereof 中国科学院大连化学物理研究所 2025-03-28 CN claimed
CN-118307780-A Polyimide toughening agent and preparation method and application thereof 中国科学院化学研究所 2024-07-09 CN claimed
CN-111116950-B High-performance polyimide film and preparation method thereof 株洲时代华鑫新材料技术有限公司 2022-08-23 CN claimed
CN-114752337-A Waterproof MS sealant and preparation method thereof 江苏瑞洋安泰新材料科技有限公司 2022-07-15 CN claimed
CN-108752594-B Amphipathic block polymer based on azo reductase response and preparation method and application thereof 苏州大学张家港工业技术研究院 2020-09-25 CN claimed
CN-111116950-A High-performance polyimide film and preparation method thereof 株洲时代华鑫新材料技术有限公司 2020-05-08 CN claimed
EP-2611797-B1 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI SCIENCE CO LTD (KR) 2016-12-28 EP claimed
US-9147603-B2 Polymer grafting for enhanced dielectric and interconnect material adhesion INTEL CORPORATION (US) 2015-09-29 US claimed
US-20150206793-A1 POLYMER GRAFTING FOR ENHANCED DIELECTRIC AND INTERCONNECT MATERIAL ADHESION INTEL CORPORATION 2015-07-23 US claimed
US-8835458-B2 Quinoline or quinazoline derivatives with apoptosis inducing activity on cells HANMI SCIENCE CO., LTD (KR) 2014-09-16 US claimed
EP-2611797-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS Hanmi Science Co., Ltd. (KR) 2013-07-10 EP claimed
US-20130165386-A1 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI SCIENCE CO., LTD (KR) 2013-06-27 US claimed
WO-2012030160-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI HOLDINGS CO., LTD. (KR) 2012-03-08 WO claimed
CN-100554251-C A kind of maleimide derivatives and preparation method thereof CHINESE ACAD INST CHEMISTRY (CN) 2009-10-28 CN claimed
CN-1896058-A Maleimide derivative and its preparation CHINESE ACAD INST CHEMISTRY (CN) 2007-01-17 CN claimed
EP-4676926-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS ThirtyFiveBio Limited (GB) 2026-01-14 EP disclosed
WO-2025096924-A2 METHODS OF LABELING, PROCESSING, AND ANALYZING PROTEIN SAMPLES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-05-08 WO disclosed
US-6573269-B1 Compounds for protecting surface of substrate from ultraviolet light ROCHE VITAMINS INC. 2003-06-03 US disclosed
EP-1081140-A2 Novel Pyrimidine-2,4,6-trione compounds F. HOFFMANN-LA ROCHE AG (CH) 2001-03-07 EP disclosed
US-3978091-A FUNGICIDES, INSECTICIDES, NEMATOCIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165386-A1 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS CASP7, API5, BAX CA12 3044/4885CA1 409/4885CA2 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.