Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20178107 | 1.00 | EPHX1 (0.51) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL1989005 | 1.00 | EPHX1 (0.51) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL12564554 | 1.00 | EPHX1 (0.51) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL1989006 | 1.00 | EPHX1 (0.51) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL28377094 | 0.92 | CPB1 (0.45) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL28380522 | 0.92 | CPB1 (0.45) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL27301394 | 0.88 | ALDH1A1 (0.50) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL28380424 | 0.87 | ALDH1A1 (0.52) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| Hydrochloric Acid SCHEMBL28376398 | 0.86 | ALDH1A1 (0.51) | EPHX1ALDH1A1KDM1AMAOBGAA | |
| SCHEMBL6612597 | 0.81 | EPHX1 (0.63) | EPHX1ALDH1A1GAACPB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489236-A1 | PROCESS FOR THE PREPARATION OF FUSED HETEROAROMATIC PYRROLIDINONES | Takeda Pharmaceutical Company Limited (JP) | 2019-05-29 | — | — | EP | disclosed |
| WO-2011079051-A1 | FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-30 | — | — | WO | disclosed |