SCHEMBL1264092

SCHEMBL1264092

O=C1C=CC(=O)N1C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578152 0.93 MGLL (0.35) LMNAGSK3AGSK3BMGLL
SCHEMBL9578159 0.90 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL9578155 0.90 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL9578119 0.87 MGLL (0.35) LMNAGSK3AGSK3BMGLL
SCHEMBL5889438 0.82 MGLL (0.35) LMNAGSK3AGSK3BMGLL
SCHEMBL9852613 0.80 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL9852591 0.76 KDM4E (0.31)
SCHEMBL21419589 0.72 MGLL (0.35) LMNAGSK3AGSK3BMGLL
SCHEMBL3482921 0.71 MGLL (0.38) LMNAGSK3AGSK3BMGLL
SCHEMBL11645947 0.66 MGLL (0.37) LMNAGSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7892454-B2 Such as 2,3:6,7-anthracenedicarboximide derivatives; air stability, solution processability; n type; organic thin film transistors, light emitting diodes and photovoltaic devices; long lasting POLYERA CORPORATION (US) 2011-02-22 US disclosed
US-20080185555-A1 Acene-based organic semiconductor materials and methods of preparing and using the same USINVEST LLC 2008-08-07 US disclosed
WO-2008063583-A1 ACENE-BASED ORGANIC SEMICONDUCTOR MATERIALS AND METHODS OF PREPARING AND USING THE SAME POLYERA CORPORATION (US) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080185555-A1 Acene-based organic semiconductor materials and methods of preparing and using the same ACE, ACE2, AGT LMNA 1210/4885GSK3A 4676/4885GSK3B 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.