SCHEMBL9852613

SCHEMBL9852613

O=C1C=CC(=O)N1C(F)(N1C(=O)C=CC1=O)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264092 0.80 LMNA (0.31) MGLLGSK3AGSK3B
SCHEMBL5889438 0.76 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL3482352 0.76 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL9578152 0.76 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL9578119 0.76 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL21419589 0.76 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL3482921 0.75 MGLL (0.38) MGLLGSK3AGSK3BFAAH
SCHEMBL9578155 0.74 MGLL (0.33) MGLLGSK3AGSK3BFAAH
SCHEMBL9578159 0.74 MGLL (0.33) MGLLGSK3AGSK3BFAAH
SCHEMBL3482453 0.69 TLR9 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0422379-A2 Thermosetting resin composition, resin sheet, prepreg and laminated sheet NITTO DENKO CORPORATION (JP) 1991-04-17 EP disclosed