Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498956 | 0.85 | KMT2A (0.42) | MEN1KMT2ALMNAALDH1A1KDM4C | |
| SCHEMBL14138278 | 0.84 | MEN1 (0.54) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL10344379 | 0.84 | MEN1 (0.54) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL27200218 | 0.84 | MEN1 (0.54) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL9316469 | 0.84 | MEN1 (0.54) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL25213709 | 0.84 | MEN1 (0.54) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL26923978 | 0.84 | MEN1 (0.53) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL16376197 | 0.83 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4CNPC1 | |
| SCHEMBL6879144 | 0.83 | MEN1 (0.52) | MEN1KMT2ALMNAKDM4CNPC1 | |
| SCHEMBL10344454 | 0.83 | MEN1 (0.52) | MEN1KMT2ALMNAKDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022235-B2 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use | CELLECTAR, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-8022235-B2 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use | CELLECTAR, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-7893286-B2 | Method for the synthesis of phospholipid ethers | CELLECTAR, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893286-B2 | Method for the synthesis of phospholipid ethers | CELLECTAR, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20090018357-A1 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use | CELL ACQUISITION CORP. | 2009-01-15 | — | — | US | disclosed |
| US-20090018357-A1 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use | CELL ACQUISITION CORP. | 2009-01-15 | — | — | US | disclosed |
| US-20080312459-A1 | Method for the synthesis of phospholipid ethers | CELL ACQUISITION CORP. | 2008-12-18 | — | — | US | disclosed |
| US-20080312459-A1 | Method for the synthesis of phospholipid ethers | CELL ACQUISITION CORP. | 2008-12-18 | — | — | US | disclosed |
| WO-2008150439-A1 | COMPOSITIONS OF PHOSPHOLIPID ETHER BORONIC ACIDS AND ESTERS AND METHODS FOR THEIR SYNTHESIS AND USE | CELLECTAR, INC. (US) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018357-A1 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use | PHOSPHO1, PEBP1, SGMS1 | MEN1 449/4885KMT2A 2096/4885LMNA 278/4885 |
| US-20080312459-A1 | Method for the synthesis of phospholipid ethers | PHOSPHO1, PLEC, PLA2G2C | MEN1 365/4885KMT2A 1176/4885LMNA 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.