Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643055 | 0.90 | TDP1 (0.39) | TDP1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2040251 | 0.82 | IDO1 (0.42) | CNR2HTTLMNARORC | |
| SCHEMBL2037470 | 0.82 | ALDH1A1 (0.42) | MAPTALDH1A1MEN1KMT2ACNR2 | |
| SCHEMBL12643061 | 0.81 | CNR2 (0.43) | TDP1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL12642956 | 0.80 | POLB (0.44) | TDP1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2036078 | 0.75 | EGFR (0.42) | MAPTMEN1KMT2AEGFRERBB2 | |
| SCHEMBL16222983 | 0.73 | POLB (0.60) | TDP1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2036160 | 0.72 | IDO1 (0.41) | CNR2HTTLMNARORC | |
| SCHEMBL2044112 | 0.71 | HTT (0.46) | CNR2HTTLMNARORC | |
| SCHEMBL2036957 | 0.71 | RORC (0.43) | MAPTALDH1A1MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079102-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |