Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484092 | 0.77 | CYP2A6 (0.36) | HTTGAACYP2A6ALDH1A1 | |
| SCHEMBL21562913 | 0.74 | KMT2A (0.41) | HTTGAAKMT2AL3MBTL1TSHR | |
| SCHEMBL17682605 | 0.74 | HTT (0.54) | HTTGAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL18896278 | 0.74 | HTT (0.59) | HTTGAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL21562909 | 0.73 | KMT2A (0.39) | HTTGAAKMT2AL3MBTL1TSHR | |
| SCHEMBL12691665 | 0.69 | CYP2C19 (0.41) | HTTGAAKMT2ATSHRALDH1A1 | |
| SCHEMBL12489633 | 0.69 | HTR2C (0.48) | HTTGAAKMT2ASMN1; SMN2POLB | |
| SCHEMBL16888281 | 0.68 | RORC (0.35) | HTTGAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL20333665 | 0.67 | HTT (0.40) | HTTGAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL12425838 | 0.67 | HPGD (0.40) | GAAL3MBTL1TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011077502-A1 | DIHYDROTHIENO[2,3-E]INDAZOLE COMPOUND | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |