Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 6/20 | 0.60 |
| ▸ | PPIB | P23284 | 5/20 | 0.60 |
| ▸ | PPIG | Q13427 | 3/20 | 0.60 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037937 | 0.90 | PPID (0.74) | PPIDPPIBPPIGPPIARAB9A | |
| SCHEMBL12643704 | 0.84 | PPID (0.64) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2035732 | 0.77 | PPIB (0.55) | PPIDPPIBPPIGPPIARAB9A | |
| SCHEMBL12643694 | 0.76 | PPID (0.61) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643831 | 0.75 | PPIB (0.51) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643698 | 0.75 | PPID (0.63) | PPIDPPIBPPIGPPIAALOX15 | |
| SCHEMBL12643824 | 0.75 | PPID (1.00) | PPIDPPIBPPIGPPIARAB9A | |
| SCHEMBL12643703 | 0.74 | PPID (0.60) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2036394 | 0.74 | PPID (0.80) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2037853 | 0.73 | PPIB (0.77) | PPIDPPIBPPIGPPIAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |