Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 6/20 | 0.64 |
| ▸ | PPIB | P23284 | 5/20 | 0.64 |
| ▸ | PPIG | Q13427 | 2/20 | 0.64 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036394 | 0.89 | PPID (0.80) | PPIDPPIBPPIGPPIAROCK2 | |
| SCHEMBL12643701 | 0.84 | PPID (0.60) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643694 | 0.79 | PPID (0.61) | PPIDPPIBPPIGPPIANAMPT | |
| SCHEMBL12643698 | 0.78 | PPID (0.63) | PPIDPPIBPPIGPPIA | |
| SCHEMBL12643824 | 0.78 | PPID (1.00) | PPIDPPIBPPIGPPIANAMPT | |
| SCHEMBL2037853 | 0.78 | PPIB (0.77) | PPIDPPIBPPIGPPIANAMPT | |
| SCHEMBL12643703 | 0.77 | PPID (0.60) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643831 | 0.77 | PPIB (0.51) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2037969 | 0.74 | PPIB (0.76) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2037937 | 0.73 | PPID (0.74) | PPIDPPIBPPIGPPIAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |