Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 5/20 | 0.47 |
| ▸ | PPID | Q08752 | 4/20 | 0.47 |
| ▸ | PPIG | Q13427 | 3/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14643175 | 0.89 | PPIB (0.49) | PPIBPPIDPPIGPPIAALDH1A1 | |
| SCHEMBL2041992 | 0.80 | PPIB (0.51) | PPIBPPIDPPIGPPIAALDH1A1 | |
| SCHEMBL28750716 | 0.69 | HDAC1 (0.77) | ALDH1A1HDAC1HDAC6GAAKMT2A | |
| SCHEMBL15939528 | 0.68 | PPID (0.65) | PPIBPPIDPPIGPPIAKMT2A | |
| SCHEMBL15832158 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HDAC1GAAKDM4ELMNA | |
| SCHEMBL12643953 | 0.68 | ALDH1A1 (0.60) | PPIBPPIDPPIGPPIAALDH1A1 | |
| SCHEMBL12643760 | 0.66 | PPID (0.63) | PPIBPPIDPPIGPPIAKMT2A | |
| SCHEMBL12643755 | 0.66 | SMN1; SMN2 (0.68) | PPIBPPIDPPIGPPIAGAA | |
| SCHEMBL12643832 | 0.65 | PPIB (0.53) | PPIBPPIDPPIGPPIAALDH1A1 | |
| SCHEMBL2044119 | 0.65 | PPID (1.00) | PPIBPPIDPPIGPPIAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |