Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | PPID | Q08752 | 2/20 | 0.48 |
| ▸ | PPIG | Q13427 | 2/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038255 | 0.91 | PPIB (0.58) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL2034561 | 0.80 | PPIB (0.76) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL2040991 | 0.80 | PPIB (0.69) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL19882147 | 0.80 | TSPO (0.53) | PPIBALDH1A1TSPOMEN1KMT2A | |
| SCHEMBL12643953 | 0.80 | ALDH1A1 (0.60) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL12643833 | 0.78 | PPIB (0.46) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL2038459 | 0.78 | PPIB (0.54) | PPIBPPIDPPIGPPIAMEN1 | |
| SCHEMBL15832171 | 0.77 | PPID (0.56) | PPIBALDH1A1PPIDPPIGPPIA | |
| SCHEMBL3815151 | 0.73 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL2041992 | 0.72 | PPIB (0.51) | PPIBALDH1A1PPIDPPIGPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |