Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620973 | 0.86 | HPGD (0.55) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL15736793 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL11881581 | 0.79 | MAOB (0.55) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL7142288 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL12456653 | 0.79 | HPGD (0.55) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL1568299 | 0.79 | HPGD (0.59) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL30493818 | 0.79 | HPGD (0.55) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL19127755 | 0.76 | HPGD (0.56) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL28004016 | 0.73 | HPGD (0.49) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL7143389 | 0.72 | HPGD (0.51) | SMN1; SMN2POLBHPGDTYRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879574-B2 | Folded peptide backbone each end of which is conjugated to a fluorophore, which when cleaved as by digestion with a protease, the fluorophores provide high intensity signals; histology | ONCOIMMUNIN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20090325168-A1 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| EP-0988394-B1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2009-12-30 | — | — | EP | disclosed |
| US-7541143-B2 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOIMMUNIN, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080199898-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-7312302-B2 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCOLMMUNIN, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1214445-A4 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-6936687-B1 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof | ONCO IMMUNIN, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| US-20050158766-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOLMMUNIN, INC. | 2005-07-21 | — | — | US | disclosed |
| US-6893868-B2 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCO IMMUNIN, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20030207264-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOLMMUNIN, INC. | 2003-11-06 | — | — | US | disclosed |
| EP-1356084-A2 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-0988394-A4 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN INC (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002061038-A9 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN INC (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002061038-A2 | HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES | ONCOIMMUNIN, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| EP-1214445-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018238-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| EP-0988394-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| US-6037137-A | FLUORESCENT COMPOUND FOR SCREENING CLEAVING ACTIVITY AND STRUCTURAL CHANGES OF ENZYMATIC PROTEINS | ONCOIMMUNIN, INC. (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1998037226-A1 | COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF | ONCOIMMUNIN, INC. (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207264-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | DNTT, HMBS, WRN | SMN1; SMN2 3740/4885POLB 285/4885HPGD 272/4885 |
| US-20050158766-A1 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | DNTT, WRN, HMBS | SMN1; SMN2 3666/4885POLB 258/4885HPGD 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.