Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265349 | 0.84 | PDE10A (0.74) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10467734 | 0.83 | ALDH1A1 (0.63) | PDE10ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26617556 | 0.82 | PDE10A (0.62) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL30682020 | 0.81 | PDE10A (0.60) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL27855178 | 0.81 | PDE10A (0.60) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7533563 | 0.81 | PDE10A (0.60) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL29402079 | 0.80 | ALDH1A1 (0.59) | PDE10ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6783762 | 0.80 | ALDH1A1 (0.59) | PDE10ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8574197 | 0.79 | HSD17B10 (0.58) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2908831 | 0.79 | ALDH1A1 (0.62) | PDE10AHTTTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884067-B2 | inhibiting tumor metastasis; for determining susceptibility to Alzheimer's disease; drug screening | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2011-02-08 | — | — | US | disclosed |
| EP-1888817-A2 | METHOD FOR PRODUCING POROUS METAL-ORGANIC FRAMEWORK MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125761-A2 | METHOD FOR PRODUCING POROUS METAL-ORGANIC FRAMEWORK MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| US-20050245453-A1 | Peptides derived from cadherin and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-03 | — | — | US | disclosed |
| WO-2003087136-A2 | PEPTIDES DERIVED FROM CADHERIN AND METHODS OF USE THEREOF | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2003-10-23 | — | — | WO | disclosed |