Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL635869 | 1.00 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL20656 | 0.96 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL27551504 | 0.96 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL7549527 | 0.96 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrogen Sulfide SCHEMBL9281216 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Bromide SCHEMBL10582038 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Water SCHEMBL1155699 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL22204469 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL809934 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL3429854 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893249-B2 | Deprotection and purification of oligonucleotides and their derivatives | SIRNA THERAPEUTICS, INC. (US) | 2011-02-22 | — | — | US | claimed |
| US-7655790-B2 | Synthesizing nucleic acid, contacting with a alkylamine, loading mixture onto media and applying a purification gradient using a suitable elution buffer; one pot deprotection; solution phase synthesis; solid phase synthesis | SIRNA THERAPEUTICS, INC. (US) | 2010-02-02 | — | — | US | claimed |
| US-6989442-B2 | Deprotection and purification of oligonucleotides and their derivatives | SIRNA THERAPEUTICS, INC. (US) | 2006-01-24 | — | — | US | claimed |
| US-20050215777-A1 | Synthesizing nucleic acid, contacting with a alkylamine, loading mixture onto media and applying a purification gradient using a suitable elution buffer; one pot deprotection; solution phase synthesis; solid phase synthesis | SIRNA THERAPEUTICS, INC. (US) | 2005-09-29 | — | — | US | claimed |
| US-20040048251-A1 | Deprotection and purification of oligonucleotides and their derivatives | SIRNA THERAPEUTICS, INC. | 2004-03-11 | — | — | US | claimed |