Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656 | 1.00 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Water SCHEMBL1155699 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Bromide SCHEMBL10582038 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL809934 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL3429854 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL7464488 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Fluoride SCHEMBL635869 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Fluoride SCHEMBL1264751 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL22204469 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrogen Sulfide SCHEMBL9281216 | 0.96 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001506611-A | — | — | 2001-05-22 | — | — | JP | claimed |
| EP-0942902-A2 | NOVEL IMMUNOTHERAPEUTIC IMIDES/AMIDES | CELGENE CORPORATION (US) | 1999-09-22 | — | — | EP | claimed |
| WO-1998024763-A2 | IMMUNOTHERAPEUTIC IMIDES/AMIDES AS PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1998-06-11 | — | — | WO | claimed |
| US-5703098-A | INHIBITORS OF CYTOKINES INCLUDING TUMOR NECROSIS FACTOR | CELGENE CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| EP-0942902-A2 | NOVEL IMMUNOTHERAPEUTIC IMIDES/AMIDES | CELGENE CORPORATION (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024763-A2 | IMMUNOTHERAPEUTIC IMIDES/AMIDES AS PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5196592-A | Rhodium containing dehydrogenation catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-5162334-A | Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | disclosed |