Fluoride

Fluoride

SCHEMBL635869

C=CCN(CC=C)CC=C.F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 3/20 0.33
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
OPRK1 P41145 2/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL1264751 1.00 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL20656 0.96 TSHR (0.43) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL27551504 0.96 TSHR (0.43) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL7549527 0.96 TSHR (0.43) TSHRALDH1A1OPRM1OPRD1OPRK1
Hydrogen Sulfide SCHEMBL9281216 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
Bromide SCHEMBL10582038 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
Water SCHEMBL1155699 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL22204469 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
Hydrochloric Acid SCHEMBL809934 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL3429854 0.92 TSHR (0.40) TSHRALDH1A1OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336851-B2 Copolymer for semiconductor lithography, resist composition, and method for manufacturing substrate MITSUBISHI CHEMICAL CORPORATION 2019-07-02 US disclosed
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
US-20160200849-A1 COPOLYMER FOR SEMICONDUCTOR LITHOGRAPHY, RESIST COMPOSITION, AND METHOD FOR MANUFACTURING SUBSTRATE MITSUBISHI RAYON CO., LTD. (JP) 2016-07-14 US disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
US-8558108-B2 Electron donating material, material for photovoltaic devices and photovoltaic device TORAY INDUSTRIES, INC. (JP) 2013-10-15 US disclosed
EP-2266982-B1 ELECTRON DONATING ORGANIC MATERIAL, MATERIAL FOR PHOTOVOLTAIC ELEMENT, AND PHOTOVOLTAIC ELEMENT TORAY INDUSTRIES (JP) 2013-09-04 EP disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20110023964-A1 ELECTRON DONATING MATERIAL, MATERIAL FOR PHOTOVOLTAIC DEVICES AND PHOTOVOLTAIC DEVICE TORAY INDUSTRIES, INC. (JP) 2011-02-03 US disclosed
EP-2266982-A1 ELECTRON DONATING ORGANIC MATERIAL, MATERIAL FOR PHOTOVOLTAIC ELEMENT, AND PHOTOVOLTAIC ELEMENT Toray Industries, Inc. (JP) 2010-12-29 EP disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed
EP-1295602-A1 OXYGEN-CONTAINING OPHTHALMIC COMPOSITION ROHTO PHARMACEUTICAL CO., LTD. (JP) 2003-03-26 EP disclosed
US-20020164379-A1 Oxygen-containing ophthalmic composition ROHTO PHARMACEUTICAL CO., LTD. (JP) 2002-11-07 US disclosed
EP-0282973-B1 CROSS-LINKING OF THERMOSETTING RESINS BY MEANS OF HEATING WITH SATURATED PERFLUOROPOLYETHER VAPOUR AUSIMONT S.r.l. (IT) 1991-05-29 EP disclosed
EP-0282973-A1 Cross-linking of thermosetting resins by means of heating with saturated perfluoropolyether vapour AUSIMONT S.r.l. (IT) 1988-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020164379-A1 Oxygen-containing ophthalmic composition OGFOD1, HIF1A, HAO2 TSHR 4566/4885ALDH1A1 1873/4885OPRM1 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.