⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535831 | 0.88 | — | — | |
| SCHEMBL1265827 | 0.83 | — | — | |
| SCHEMBL6412835 | 0.78 | HSD17B10 (0.32) | — | |
| Trimethylammonium SCHEMBL27395135 | 0.74 | — | — | |
| SCHEMBL18686399 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL5586074 | 0.74 | KDM4E (0.34) | — | |
| SCHEMBL18632113 | 0.73 | — | — | |
| SCHEMBL2138361 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL17580303 | 0.72 | ALDH1A1 (0.39) | — | |
| Water SCHEMBL28778494 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-7880017-B2 | Made by reacting a cyano compound with a silylalkylisocyanide compound; silylimidazole ; | ALLERGAN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7880017-B2 | Made by reacting a cyano compound with a silylalkylisocyanide compound; silylimidazole ; | ALLERGAN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7880017-B2 | Made by reacting a cyano compound with a silylalkylisocyanide compound; silylimidazole ; | ALLERGAN, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7598394-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598394-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598394-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
| US-7183305-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183305-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183305-B2 | Process for the synthesis of imidazoles | ALLERGAN, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| EP-1682517-A1 | PROCESS FOR THE SYNTHESIS OF IMIDAZOLES | Allergan, Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005047267-A1 | PROCESS FOR THE SYNTHESIS OF IMIDAZOLES | ALLERGAN, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20050101785-A1 | Process for the synthesis of imidazoles | ALLERGAN, INC. | 2005-05-12 | — | — | US | disclosed |
| EP-0500653-A4 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| US-4985434-A | 7-substituted derivatives of 2-amino-3H,5H-pyrrolo(3,2-d)pyrimidin-4-ones and pharamceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1991-01-15 | — | — | US | disclosed |