SCHEMBL2138361

SCHEMBL2138361

C1=CCC(CC2CC=CCC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 8/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
PKM P14618 1/20 0.35
CDK1 P06493 2/20 0.35
CCNB1 P14635 2/20 0.35
CCNA2 P20248 2/20 0.35
CDK2 P24941 2/20 0.35
CCNA1 P78396 2/20 0.35
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524754 0.95 ALDH1A1 (0.36) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL1524849 0.88 KDM4E (0.41) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL3546900 0.84 KDM4E (0.34) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL17580303 0.82 ALDH1A1 (0.39) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL14302993 0.81 MAPK1 (0.37) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL5384642 0.81 KDM4E (0.33) KDM4EHSD17B10MAPK1LMNA
SCHEMBL1525295 0.78 ALDH1A1 (0.36) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL2136195 0.78 MAPK1 (0.38) ALDH1A1ALOX15KDM4EHSD17B10MAPK1
SCHEMBL8346743 0.78
SCHEMBL8239080 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
US-20240166815-A1 POLYMERIC AMINO (METH)ACRYLATE ALLNEX BELGIUM, S.A. (BE) 2024-05-23 US disclosed
EP-3929256-B1 POLYMERIC AMINO (METH)ACRYLATE ALLNEX Belgium SA (BE) 2024-01-24 EP disclosed
EP-2560948-B2 RADIATION CURABLE AMINO(METH)ACRYLATES ALLNEX Belgium SA (BE) 2023-07-12 EP disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-20230151222-A1 AMINO (METH)ACRYLATES ALLNEX BELGIUM S.A. (BE) 2023-05-18 US disclosed
CN-110621653-B Amino (meth) acrylates 湛新比利时股份有限公司 2022-09-16 CN disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-1575909-A1 PROCESS FOR PRODUCING CARBAMOYLOXY (METH)ACRYLATES AND NEW CARBAMOYLOXY (METH)ACRYLATES SURFACE SPECIALTIES, S.A. (BE) 2005-09-21 EP disclosed
US-20050113594-A1 Process using a cyclic carbonate reactant SURFACE SPECIALTIES, S.A. (BE) 2005-05-26 US disclosed
US-20040242839-A1 Method of producing epoxy compound, epoxy resin composition and its applications, ultraviolet rays-curable can-coating composition and method of producing coated metal can TAKAI HIDEYUKI (JP) 2004-12-02 US disclosed
US-20040236119-A1 Process using a cyclic carbonate reactant and beta-hydroxyurethanes thereby obtained SURFACE SPECIALTIES, S.A. (BE) 2004-11-25 US disclosed
EP-1474383-A1 PROCESS USING A CYCLIC CARBONATE REACTANT UCB, S.A. (BE) 2004-11-10 EP disclosed
EP-1471053-A2 Process using a cyclic carbonate reactant and beta-hydroxyurethanes thereby obtained UCB S.A. (BE) 2004-10-27 EP disclosed
WO-2004052843-A1 PROCESS FOR PRODUCING CARBAMOYLOXY (METH)ACRYLATES AND NEW CARBAMOYLOXY (METH)ACRYLATES SURFACE SPECIALTIES, S.A. (BE) 2004-06-24 WO disclosed
EP-1389615-A1 PROCESS FOR PRODUCING EPOXY COMPOUND, EPOXY RESIN COMPOSITION AND USE THEREOF, ULTRAVIOLET-CURABLE CAN COATING COMPOSITION, AND PROCESS FOR PRODUCING COATED METAL CAN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2004-02-18 EP disclosed
WO-2003066580-A1 PROCESS USING A CYCLIC CARBONATE REACTANT UCB, S.A. (BE) 2003-08-14 WO disclosed
US-20030059618-A1 Method of producing epoxy compound, epoxy resin composition and its applications, ultraviolet rays-curable can-coating composition and method of producing coated metal can DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236119-A1 Process using a cyclic carbonate reactant and beta-hydroxyurethanes thereby obtained UROD, PCNA, OGG1 ALDH1A1 1090/4885ALOX15 982/4885KDM4E 711/4885
US-20050113594-A1 Process using a cyclic carbonate reactant UROD, PCNA, UGP2 ALDH1A1 2969/4885ALOX15 770/4885KDM4E 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.