⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891295 | 0.90 | — | — | |
| SCHEMBL16499515 | 0.88 | — | — | |
| SCHEMBL6261176 | 0.64 | — | — | |
| SCHEMBL3477128 | 0.63 | — | — | |
| SCHEMBL27399684 | 0.61 | CA2 (0.41) | — | |
| SCHEMBL27494881 | 0.61 | — | — | |
| SCHEMBL829063 | 0.61 | — | — | |
| SCHEMBL14335539 | 0.61 | — | — | |
| SCHEMBL6506759 | 0.60 | — | — | |
| SCHEMBL22280384 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775382-A | Preparation method of pyrazole alkanol compound | UNIV NINGBO | 2012-11-14 | — | — | CN | claimed |
| CN-102775390-A | Pyrazolidine alcohol compound and preparation method thereof | UNIV NINGBO | 2012-11-14 | — | — | CN | claimed |
| EP-2155202-A2 | 3,6-DISUBSTITUTED-IMIDAZO[1,2-B]PYRIDAZINES AND 3,5-DISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS | Novartis Ag (CH) | 2010-02-24 | — | — | EP | claimed |
| WO-2008138889-A2 | 3, 6-DISUBSTITUTED-IMIDAZO [1, 2-B] PYRIDAZINES AND 3, 5-DISUBSTITUTED PYRAZOLO[1, 5-A] PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS | NOVARTIS AG (CH) | 2008-11-20 | — | — | WO | claimed |
| US-20080287390-A1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2008-11-20 | — | — | US | claimed |
| EP-1426361-B1 | Novel composition containing a bi-cyclic compound and a glyceride | SUCAMPO AG (CH) | 2008-07-30 | — | — | EP | claimed |
| US-20070037772-A1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2007-02-15 | — | — | US | claimed |
| US-20040152751-A1 | Pyrazolidinol compounds | TJOTTA ENOK (NO) | 2004-08-05 | — | — | US | claimed |
| JP-2003503389-A | — | — | 2003-01-28 | — | — | JP | claimed |
| EP-1194409-A1 | PYRAZOLIDINOL COMPOUNDS | A-Viral AS (NO) | 2002-04-10 | — | — | EP | claimed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | claimed |
| WO-2023132369-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT | 中外製薬株式会社 | 2023-07-13 | — | — | WO | disclosed |
| US-20210284627-A1 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2021-09-16 | — | — | US | disclosed |
| EP-3766877-A1 | INDOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2021-01-20 | — | — | EP | disclosed |
| CN-105085406-B | Benzimidazole ring-containing propiolamide derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-11-03 | — | — | CN | disclosed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | disclosed |
| US-5928393-A | ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES | NIPPON OIL CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| CN-1172847-A | Fuel additive | NIPPON OIL CO LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
| EP-0819753-A1 | Fuel additive | NIPPON OIL CO. LTD. (JP) | 1998-01-21 | — | — | EP | disclosed |