Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323442 | 0.92 | CA2 (0.44) | CA2CHKAMMP3DPP4CA12 | |
| SCHEMBL829063 | 0.83 | — | — | |
| SCHEMBL27508934 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL10986584 | 0.81 | — | — | |
| SCHEMBL4068512 | 0.79 | — | — | |
| SCHEMBL16611544 | 0.79 | — | — | |
| SCHEMBL6689416 | 0.79 | CA2 (0.33) | CA2CHKAMMP3DPP4CA12 | |
| SCHEMBL5544301 | 0.79 | — | — | |
| SCHEMBL7458218 | 0.76 | — | — | |
| SCHEMBL3466500 | 0.74 | CA2 (0.43) | CA2CHKAMMP3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187904-A | 2-phenylimidazole analog derivative containing propioloyl amido and preparation method thereof and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2016-12-07 | — | — | CN | claimed |
| CN-105593217-A | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL CO | 2016-05-18 | — | — | CN | claimed |
| CN-101541783-B | pyridinonyl PDK1 inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2014-10-01 | — | — | CN | claimed |
| CN-102203089-A | N-sulfonylamino polycyclic pyrazolyl compounds | ELAN PHARM INC | 2011-09-28 | — | — | CN | claimed |
| CN-101171248-A | 3-mono- and 3,5-disubstituted piperidine derivatives as renin inhibitors | NOVARTIS AG (CH) | 2008-04-30 | — | — | CN | claimed |
| CN-101133025-A | Organic compounds | NOVARTIS AG (CH) | 2008-02-27 | — | — | CN | claimed |
| CN-101103002-A | 3,4,(5)-substituted tetrahydropyridines | NOVARTIS AG (CH) | 2008-01-09 | — | — | CN | claimed |
| CN-101094848-A | Organic compounds | NOVARTIS AG (CH) | 2007-12-26 | — | — | CN | claimed |
| CN-1110482-C | Carboxyl acid substituted heterocycles as metalloproteinase inhibitors | AMGEN INC (US) | 2003-06-04 | — | — | CN | claimed |
| CN-1284947-A | Carboxyl acid substituted heterocycles as metalloproteinase inhibitors | AMGEN INC (US) | 2001-02-21 | — | — | CN | claimed |
| CN-108362881-A | A kind of colloidal gold of pyrazolone ntipyretic analgesic medicine quickly examines test device and its preparation method and application | 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） | 2018-08-03 | — | — | CN | disclosed |
| CN-108148060-A | Substituted heterocyclic compound and its derivative, pharmaceutical composition, Preparation method and use | 四川科伦博泰生物医药股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-105593217-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2018-05-25 | — | — | CN | disclosed |
| CN-106187904-A | 2-phenylimidazole analog derivative containing propioloyl amido and preparation method thereof and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2016-12-07 | — | — | CN | disclosed |
| CN-103702665-B | For inflammation and the compound of immune-related uses | 幸讬制药公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-1246857-A | Substituted pyrimidinone and pyridinone compounds and their use | AMGEN INC (US) | 2000-03-08 | — | — | CN | disclosed |
| CN-1237159-A | Enantiomerically pure basic aryl-cycloalkyl-hydroxycarboxylic esters, process for their preparation and their use in medicaments | CHRISTIAN R NOE (DE) | 1999-12-01 | — | — | CN | disclosed |
| CN-1208409-A | Novel benzoyl guanidine derivatives process for their preparation and their use in the preparation of medicines | BOEHRINGER INGELHEIM KG (DE) | 1999-02-17 | — | — | CN | disclosed |
| CN-1204315-A | Novel phenylamidine derivatives, process for preparing same and use thereof as pharmaceutical composition | BOEHRINGER INGELHEIM KG (DE) | 1999-01-06 | — | — | CN | disclosed |
| CN-1199181-A | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1998-11-18 | — | — | CN | disclosed |