Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9126637 | 0.86 | ALDH1A1 (0.37) | HRH3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8831929 | 0.86 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL12650828 | 0.79 | — | — | |
| SCHEMBL17791197 | 0.75 | ALDH1A1 (0.37) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10984519 | 0.72 | GRIN2B (0.50) | ALDH1A1GAAMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL10984786 | 0.72 | SLC18A3 (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL31553311 | 0.72 | KDM4E (0.35) | HRH3KDM4EALDH1A1 | |
| SCHEMBL10984496 | 0.70 | HPGD (0.47) | ALDH1A1HPGDPOLB | |
| SCHEMBL10991173 | 0.70 | MEN1 (0.48) | KDM4EALDH1A1POLB | |
| SCHEMBL10981314 | 0.70 | ADRB1 (0.44) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943605-B2 | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses | UCB PHARMA S.A. (BE) | 2011-05-17 | — | — | US | disclosed |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | COASY, FURIN, PEPD | HRH3 3883/4885KDM4E 2604/4885ALDH1A1 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.