Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MARK4 | Q96L34 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312213 | 0.83 | CYP1A2 (0.67) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12651564 | 0.82 | TUBB4A (0.46) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1786995 | 0.82 | KMT2A (0.55) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12651562 | 0.80 | NPC1 (0.43) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1791855 | 0.79 | ALDH1A1 (0.67) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21712552 | 0.76 | ALDH1A1 (0.67) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6409798 | 0.71 | CYP1A2 (0.66) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579818 | 0.70 | CYP1A2 (0.54) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8310543 | 0.70 | CYP1A2 (0.56) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL196599 | 0.70 | KMT2A (1.00) | KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124632-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | ABBOTT LABORATORIES (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124632-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | PACSIN2, MAP4K2, MAP3K6 | KMT2A 2567/4885SMN1; SMN2 2442/4885CYP1A2 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.