Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162887 | 1.00 | ANPEP (0.43) | ANPEPIL1RNERAP2ERAP1CYP2A6 | |
| SCHEMBL18761356 | 1.00 | ANPEP (0.43) | ANPEPIL1RNERAP2ERAP1CYP2A6 | |
| Hydrochloric Acid SCHEMBL11589408 | 0.98 | ANPEP (0.44) | ANPEPIL1RNERAP2ERAP1CYP2A6 | |
| Hydrochloric Acid SCHEMBL11601512 | 0.98 | ANPEP (0.44) | ANPEPIL1RNERAP2ERAP1CYP2A6 | |
| SCHEMBL15129175 | 0.79 | S100A4 (0.53) | ANPEPMAOBS100A4 | |
| SCHEMBL14855914 | 0.79 | S100A4 (0.53) | ANPEPMAOBS100A4 | |
| SCHEMBL1989836 | 0.79 | S100A4 (0.53) | ANPEPMAOBS100A4 | |
| SCHEMBL21085601 | 0.78 | CES1 (0.52) | ANPEPIL1RNERAP2ERAP1MAOA | |
| Hydrochloric Acid SCHEMBL1987878 | 0.78 | S100A4 (0.52) | ANPEPMAOBS100A4 | |
| Hydrochloric Acid SCHEMBL1995427 | 0.78 | S100A4 (0.52) | ANPEPMAOBS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712128-A1 | PHOTOCHEMICAL INTERMOLECULAR AMINATION METHOD | Fundació Institut Català d'Investigació Química (ICIQ) (ES) | 2020-09-23 | — | — | EP | disclosed |
| US-7884109-B2 | immunosuppressants such as 2-(6-Fluoro-1H-benzo[d]imidazol-1-yl)-9-((1R,4R)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)-7H-purin-8(9H)-one, used for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection | WYETH LLC (US) | 2011-02-08 | — | — | US | disclosed |
| US-7662811-B2 | N-(((5R)-5-((1-methylethyl)amino)-5,6,7,8-tetrahydro-2-naphthalenyl)methyl)-2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-1,2,3,4-tetrahydro-2-pyrazinyl)acetamide; for treatment of pain and diseases, such as inflammation mediated diseases | AMGEN INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080287468-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20070021443-A1 | Purine and imidazopyridine derivatives for immunosuppression | WYETH LLC | 2007-01-25 | — | — | US | disclosed |
| US-20060025400-A1 | 1,2,3,4-Tetrahydropyrazin-2-yl acetamides and methods of use | AMGEN INC. | 2006-02-02 | — | — | US | disclosed |
| CN-1616432-A | Compound,its use and pharmaceutical compositions comprising same | ELAN PHARM INC (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1171878-C | Compounds, their use and pharmaceutical compositions containing them | ������˹ҩƷ��˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1242007-A | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds | ELAND PHARMACEUTICAL CORP (US) | 2000-01-19 | — | — | CN | disclosed |
| US-4254268-A | OXIDIZED BY POTASSIUM PERMANGANATE | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4091018-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4089976-A | Synthesis of 1,2,3,4-tetrahydro-4-oxo-[or oxy-]-1-naphthylureas as novel growth-promoting compounds for animals | AMERICAN CYANAMID COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4088786-A | Method for utilizing tetrahydro-4-imino-1-naphthylureas as growth promoting agents for animals | AMERICAN CYANAMID COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4076952-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4075228-A | INTERMEDIATES FOR ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4072711-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
| US-4051183-A | 1-BENZOYL-3-(1,2,3,4-TETRAHYDRO-4-OXO-1-NAPHTHYL)-UREA, A NOVEL AND USEFUL INTERMEDIATE FOR THE PREPARATION OF ANIMAL GROWTH PROMOTING AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4049717-A | INTERMEDIATES FOR UREAS AND THIOUREAS | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4041070-A | ANIMAL GROWTH PROMOTERS, ENHANCING FEED EFFICIENCY | AMERICAN CYANAMID COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-3993677-A | ANIMAL GROWTH REGULATORS, HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025400-A1 | 1,2,3,4-Tetrahydropyrazin-2-yl acetamides and methods of use | AADAC, PTGES2, LTC4S | ANPEP 936/4885IL1RN 469/4885ERAP2 335/4885 |
| US-20070021443-A1 | Purine and imidazopyridine derivatives for immunosuppression | TPMT, P2RY4, P2RY1 | ANPEP 539/4885IL1RN 138/4885ERAP2 145/4885 |
| US-20080287468-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | TPMT, P2RY4, P2RY1 | ANPEP 539/4885IL1RN 138/4885ERAP2 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.