Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12165054 | 0.83 | ALOX5AP (0.34) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12165104 | 0.82 | MEN1 (0.38) | — | |
| SCHEMBL12164883 | 0.82 | SCN9A (0.37) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164888 | 0.82 | SCN9A (0.37) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12165365 | 0.82 | GABRA1 (0.35) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164937 | 0.82 | BACE1 (0.36) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164952 | 0.82 | RAB9A (0.37) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164960 | 0.82 | MEN1 (0.39) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164884 | 0.82 | SCN9A (0.37) | P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL12164887 | 0.80 | P2RX1 (0.40) | P2RX1P2RX3P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053697-A1 | 2-AMINOINDOLE COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | GENZYME CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |