Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cis-2-Penten-1-Ol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29790971 | 0.88 | LPAR3 (0.46) | LPAR2LPAR3LPAR1ALDH1A1CYP19A1 | |
| Cis-2-Penten-1-Ol SCHEMBL96103 | 0.85 | — | — | |
| Phosphoric Acid SCHEMBL7639279 | 0.85 | KDM4E (0.35) | GABRR1CA2 | |
| Cis-2-Penten-1-Ol SCHEMBL242085 | 0.85 | — | — | |
| SCHEMBL23327089 | 0.77 | ALDH1A1 (0.41) | LPAR2LPAR3LPAR1ALDH1A1CYP19A1 | |
| SCHEMBL15809764 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| SCHEMBL15809762 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| SCHEMBL162446 | 0.77 | ALDH1A1 (0.41) | LPAR2LPAR3LPAR1ALDH1A1CYP19A1 | |
| SCHEMBL20839272 | 0.77 | ALDH1A1 (0.41) | LPAR2LPAR3LPAR1ALDH1A1CYP19A1 | |
| SCHEMBL25271398 | 0.77 | ALDH1A1 (0.41) | LPAR2LPAR3LPAR1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048391-A1 | ARTIFICIAL CHROMOPLAST BIOGENESIS | CRAG - CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UB-UAB (ES) | 2021-03-18 | — | — | WO | claimed |
| EP-3792353-A1 | ARTIFICIAL CHROMOPLAST BIOGENESIS | CRAG - Centre de Recerca en Agrigenomica CSIC-IRTA-UB-UAB (ES) | 2021-03-17 | — | — | EP | claimed |
| US-20170191042-A1 | CYTOKININ SYNTHASE ENZYMES, CONSTRUCTS, AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | US | claimed |
| EP-3146055-A2 | CYTOKININ SYNTHASE ENZYMES, CONSTRUCTS, AND RELATED METHODS | Dow AgroSciences LLC (US) | 2017-03-29 | — | — | EP | claimed |
| US-20160076010-A1 | CYTOKININ SYNTHASE ENZYMES, CONSTRUCTS, AND RELATED METHODS | CORTEVA AGRISCIENCE LLC | 2016-03-17 | — | — | US | claimed |
| WO-2015179621-A2 | CYTOKININ SYNTHASE ENZYMES, CONSTRUCTS, AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-11-26 | — | — | WO | claimed |
| CN-117871718-A | Extraction and determination method and application of MEcPP compound in plant | 湖北大学 | 2024-04-12 | — | — | CN | disclosed |
| US-20230243750-A1 | RAMAN OPTICAL BIOMARKER FOR SHADE AVOIDANCE SYNDROME IN PLANTS | TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) | 2023-08-03 | — | — | US | disclosed |
| US-20220243236-A1 | PRODUCTION OF CANNABINOIDS USING GENETICALLY ENGINEERED PHOTOSYNTHETIC MICROORGANISMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-08-04 | — | — | US | disclosed |
| CN-113151316-B | Method for improving heat resistance of plants by controlling content of MECPP (mecPP) through controlling HDS22 gene | 湖北大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113151316-A | Method for regulating and controlling content of MECPP (MEcPP) by controlling HDS22 gene so as to improve heat resistance of plants | 湖北大学 | 2021-07-23 | — | — | CN | disclosed |
| WO-2021048391-A1 | ARTIFICIAL CHROMOPLAST BIOGENESIS | CRAG - CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UB-UAB (ES) | 2021-03-18 | — | — | WO | disclosed |
| EP-3792353-A1 | ARTIFICIAL CHROMOPLAST BIOGENESIS | CRAG - Centre de Recerca en Agrigenomica CSIC-IRTA-UB-UAB (ES) | 2021-03-17 | — | — | EP | disclosed |
| EP-1984492-A2 | SOYBEAN ISOPENTENYL TRANSFERASE GENES AND METHODS OF USE | Pioneer Hi-Bred International Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070245425-A1 | transgenic plant; mproves the stress tolerance; maintains or increases the size of the plant; minimizes seed abortion; increases or maintains seed set; increases shoot growth; increases seed size or seed weight; increases plant yield or plant vigor; modulates floral development; delays senescence | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2007090143-A2 | SOYBEAN ISOPENTENYL TRANSFERASE GENES AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| CN-1995355-A | Southernwood 1-hydroxy-2-methyl-2-(E)- cyclobutenyl 4-diphosphoric acid reductase protein encoding sequence | UNIV SOUTHWEST (CN) | 2007-07-11 | — | — | CN | disclosed |
| EP-1799832-A2 | ISOPENTENYL TRANSFERASE SEQUENCES AND METHODS OF USE | Pioneer-Hi-Bred International, Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034286-A2 | ISOPENTENYL TRANSFERASE SEQUENCES AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060064786-A1 | Isopentenyl transferase sequences and methods of use | PIONEER HI-BRED INTERNATIONAL, INC. | 2006-03-23 | — | — | US | disclosed |