Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12654939 | 0.91 | ANPEP (0.41) | TAS1R3TAS1R1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12654919 | 0.86 | MAPT (0.43) | TAS1R3TAS1R1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1274001 | 0.86 | POLB (0.41) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL2065133 | 0.83 | PPARG (0.39) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL12621370 | 0.82 | CTSK (0.48) | MEN1KMT2A | |
| SCHEMBL31435784 | 0.79 | BTN3A1 (0.45) | SMN1; SMN2ADAM17MMP1MMP3MMP9 | |
| SCHEMBL1274173 | 0.78 | FAAH (0.39) | CNR1 | |
| SCHEMBL12467482 | 0.77 | HPRT1 (0.46) | NPC1RAB9AL3MBTL1POLBMEN1 | |
| SCHEMBL12467473 | 0.76 | BTN3A1 (0.45) | L3MBTL1HDAC3 | |
| SCHEMBL21158536 | 0.76 | BTN3A1 (0.45) | L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951787-B2 | Phosphoramidate compounds and methods of use | CARDIFF PROTIDES LIMITED (GB) | 2011-05-31 | — | — | US | disclosed |