Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233644 | 0.82 | PSIP1 (0.50) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL479327 | 0.81 | PSIP1 (0.53) | PSIP1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3323107 | 0.79 | PSIP1 (0.52) | PSIP1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27489390 | 0.78 | SMN1; SMN2 (0.58) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6232014 | 0.77 | SMN1; SMN2 (0.53) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29563275 | 0.77 | SMN1; SMN2 (0.53) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL26416944 | 0.75 | CA12 (0.57) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8346697 | 0.75 | MAPT (0.56) | MAPTHTTL3MBTL1GAALMNA | |
| SCHEMBL10798671 | 0.74 | CHEK1 (0.54) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4629056 | 0.74 | RAB9A (0.51) | PSIP1MAPTHTTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316829-A1 | Heterocyclic derivatives as modulators of ion channels | Vertex Pharmaceuticals Incorporated (US) | 2011-05-04 | — | — | EP | disclosed |
| US-7456222-B2 | Anti tubercular drug: compositions and methods | SEQUELLA, INC. (US) | 2008-11-25 | — | — | US | disclosed |