Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823731 | 0.91 | ADRB2 (0.70) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL1824439 | 0.91 | ADRB2 (0.69) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL1822791 | 0.88 | ADRB2 (0.71) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL1821529 | 0.82 | ADRB2 (0.71) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL1824694 | 0.80 | ADRB2 (0.68) | ADRB2ADRB1 | |
| SCHEMBL1829648 | 0.79 | ADRB2 (0.67) | ADRB2ADRB1 | |
| SCHEMBL1826799 | 0.78 | ADRB2 (0.68) | ADRB2ADRB1 | |
| SCHEMBL1825263 | 0.77 | ADRB2 (0.71) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL1822773 | 0.77 | ADRB1 (0.69) | ADRB2ADRB1 | |
| SCHEMBL12657165 | 0.77 | ADRB2 (0.49) | ADRB2ADRB1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761509-B1 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2011-05-04 | — | — | EP | disclosed |