Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255005 | 0.68 | BRD4 (0.44) | BRD4BCHEACHENOS2MEN1 | |
| SCHEMBL68581 | 0.68 | MEN1 (0.61) | BRD4BCHEACHENOS2MEN1 | |
| SCHEMBL1617927 | 0.68 | PDPK1 (0.59) | BRD4BCHEACHENOS2MEN1 | |
| SCHEMBL11802702 | 0.68 | BRD4 (0.44) | BRD4BCHEACHENOS2MEN1 | |
| SCHEMBL1495908 | 0.67 | BRD4 (0.47) | BRD4BCHEACHENOS2MEN1 | |
| Hydrochloric Acid SCHEMBL7142299 | 0.67 | MEN1 (0.59) | BRD4BCHEACHEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5512697 | 0.67 | MEN1 (0.59) | BRD4BCHEACHEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29473284 | 0.67 | MEN1 (0.59) | BRD4BCHEACHEMEN1ALDH1A1 | |
| SCHEMBL17349171 | 0.67 | NOS2 (0.37) | BRD4NOS2MEN1ALDH1A1KMT2A | |
| SCHEMBL13950048 | 0.66 | BRD4 (0.42) | BRD4BCHEACHENOS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316469-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316468-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2266590-A2 | Active agent delivery sytems and methods for protecting and administering active agents | Shire LLC (US) | 2010-12-29 | — | — | EP | disclosed |