Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | MPI | P34949 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29473284 | 0.98 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL7142299 | 0.98 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL5512697 | 0.98 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL30205268 | 0.96 | MEN1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL641073 | 0.88 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL6137124 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Lactic Acid SCHEMBL30205441 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDLMNA | |
| Tert-Butyl Formate SCHEMBL27766278 | 0.82 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL31230424 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL31230416 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1086 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589448-A | 3, 4-dihydroquinolinone derivative and application thereof | 西南交通大学 | 2023-08-15 | — | — | CN | claimed |
| CN-113788828-B | Preparation method and application of isofraxine analogue from norfloxacin to isofraxine analogue | 黄河水利职业技术学院 | 2023-06-30 | — | — | CN | claimed |
| CN-113912603-B | Preparation method and application of isofraxine analogue from ciprofloxacin to isofraxine analogue | 河南大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114276369-B | Preparation method and application of isobaicine analogue from ofloxacin to isobaicine analogue | 河南大学 | 2023-05-23 | — | — | CN | claimed |
| CN-113801140-B | Preparation method and application of isofraxine analogue from levofloxacin to isofraxine analogue | 黄河水利职业技术学院 | 2023-05-23 | — | — | CN | claimed |
| CN-113956251-B | Preparation method and application of isofraxine analogue from lomefloxacin to isofraxine analogue | 河南大学 | 2023-05-23 | — | — | CN | claimed |
| CN-114276346-B | Isobanchamine analogue, preparation method and application of same from fleroxacin to | 河南大学 | 2023-05-23 | — | — | CN | claimed |
| CN-113896727-B | Preparation method and application of isofraxine analogue from gatifloxacin to isofraxine analogue | 河南大学 | 2023-05-23 | — | — | CN | claimed |
| CN-114539252-A | 2, 3-dihydroquinoline-4-ketone bioactive skeleton and synthesis method and application thereof | 山东瀚华工程设计有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-3983078-A1 | NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-04-20 | — | — | EP | claimed |
| CN-85100796-A | The preparation method of qualone derivative | — | 1986-10-01 | — | — | CN | claimed |
| US-4593101-A | Process for the preparation of 4-quinolinones | RHONE-POULENC SANTE (FR) | 1986-06-03 | — | — | US | claimed |
| EP-0097585-B1 | PROCESS FOR THE PREPARATION OF 4-HYDROXY QUINOLINES | RHONE-POULENC SANTE (FR) | 1986-03-26 | — | — | EP | claimed |
| EP-0056765-B1 | PREPARATION OF 4-HYDROXYQUINOLINES | RHONE-POULENC SANTE (FR) | 1985-06-19 | — | — | EP | claimed |
| US-4508902-A | OXIDATION OF 1,2,3,4-TETRAHYDROQUINOLINE-4-ONES | RHONE-POULENC SANTE (FR) | 1985-04-02 | — | — | US | claimed |
| EP-0056763-B1 | PROCESS FOR THE PREPARATION OF 4-QUINOLINONES | RHONE-POULENC SANTE (FR) | 1984-07-04 | — | — | EP | claimed |
| US-4412076-A | Preparation of 4-hydroxyquinolines | RHONE-POULENC SANTE (FR) | 1983-10-25 | — | — | US | claimed |
| US-4412075-A | Process for the preparation of quinolin-4-ones | RHONE-POULENC SANTE (FR) | 1983-10-25 | — | — | US | claimed |
| US-3992386-A | 4(Quinolyl)phenoxy alkanoic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-11-16 | — | — | US | claimed |
| US-3976651-A | BACTERICIDE | RIKER LABORATORIES, INC. (US) | 1976-08-24 | — | — | US | claimed |