Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.57 |
| ▸ | CA1 | P00915 | 14/20 | 0.56 |
| ▸ | CA2 | P00918 | 14/20 | 0.56 |
| ▸ | CA12 | O43570 | 6/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657220 | 0.84 | CA9 (0.58) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17067944 | 0.81 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12464674 | 0.79 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL2742845 | 0.79 | CA9 (0.58) | CA9CA1CA2CA12CA14 | |
| SCHEMBL30887118 | 0.79 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| 5-Iodoacetamidofluorescein SCHEMBL10146553 | 0.79 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14527509 | 0.79 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12793932 | 0.79 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14426895 | 0.79 | USP2 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL16421785 | 0.78 | CA9 (0.61) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319855-A1 | Bioconjugation of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2256133-A1 | Bioconjugation of macromolecules | Sigma-Aldrich Co. (US) | 2010-12-01 | — | — | EP | disclosed |