Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.61 |
| ▸ | CA1 | P00915 | 14/20 | 0.61 |
| ▸ | CA2 | P00918 | 14/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 6/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527509 | 0.88 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL16421785 | 0.88 | CA9 (0.61) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL18559017 | 0.88 | CA9 (0.60) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL2742845 | 0.86 | CA9 (0.58) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL12793932 | 0.86 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| 5-Iodoacetamidofluorescein SCHEMBL10146553 | 0.86 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL14426895 | 0.86 | USP2 (0.68) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL15150500 | 0.86 | CA9 (0.59) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL15145504 | 0.86 | CA9 (0.63) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL18595016 | 0.85 | CA9 (0.59) | CA9CA1CA2USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2378288-B1 | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST (US) | 2015-09-09 | — | — | EP | disclosed |