SCHEMBL12657983

SCHEMBL12657983

N=NC(OC(=O)CCC(=O)O)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.34
KDM6B O15054 1/20 0.34
KDM5C P41229 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
LMNA P02545 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13704735 0.77 LMNA (0.51) LMNA
SCHEMBL15671203 0.73 EGLN1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL12019111 0.73 EGLN1 (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL28910045 0.70 LMNA (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL17376887 0.68 EGLN1 (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11991261 0.68 EGLN1 (0.32) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL3732586 0.66 LMNA (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL24454652 0.65 EGLN1 (0.48) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL191308 0.65 LMNA (0.54) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL1162348 0.65 LMNA (0.45) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2101217-B1 Sulfonium salt-containing polymer, resist compositon, and patterning process SHINETSU CHEMICAL CO (JP) 2011-05-11 EP disclosed