⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19597414 | 0.46 | — | — | |
| SCHEMBL18559313 | 0.45 | PDGFRA (0.30) | — | |
| SCHEMBL16887890 | 0.45 | — | — | |
| SCHEMBL3553024 | 0.44 | CSNK2A2 (0.38) | — | |
| SCHEMBL14389637 | 0.44 | — | — | |
| SCHEMBL8265754 | 0.43 | — | — | |
| SCHEMBL3017199 | 0.43 | PBRM1 (0.39) | — | |
| SCHEMBL15511236 | 0.42 | GPR35 (0.49) | — | |
| SCHEMBL12332682 | 0.41 | — | — | |
| SCHEMBL19266074 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |