Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070979 | 0.93 | PDE2A (0.49) | PDE2AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL205534 | 0.88 | PDE2A (0.56) | PDE2AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL19417396 | 0.82 | MAPT (0.40) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL16797962 | 0.81 | NPSR1 (0.64) | PDE2AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL26766495 | 0.80 | ESR2 (0.50) | PDE2AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL26768842 | 0.80 | PDE2A (0.77) | PDE2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL14163793 | 0.77 | ESR2 (0.54) | PDE2AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL29853658 | 0.77 | PDE2A (0.77) | PDE2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL15388144 | 0.77 | PDE2A (0.77) | PDE2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL12673559 | 0.76 | MAPT (0.45) | PDE2AMAPTKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325225-A1 | Complex aryl copolymer compounds and polymer light emitting devices made by using the same | Sumitomo Chemical Company, Limited (JP) | 2011-05-25 | — | — | EP | disclosed |