Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658735 | 0.76 | PDE2A (0.49) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL13070979 | 0.73 | PDE2A (0.49) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL862799 | 0.66 | PDE2A (0.56) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL24564907 | 0.66 | MAPT (0.50) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL13647550 | 0.65 | S100A4 (0.38) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL12847193 | 0.65 | ELANE (0.70) | ALDH1A1KDM4EPOLBNPC1RAB9A | |
| SCHEMBL23693576 | 0.63 | CREBBP (0.47) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13924644 | 0.63 | CDC25A (0.54) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL803408 | 0.63 | PDE2A (1.00) | MAPTALDH1A1KDM4EPOLBPDE2A | |
| SCHEMBL29401099 | 0.63 | PDE2A (1.00) | MAPTALDH1A1KDM4EPOLBPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325223-A1 | Complex aryl copolymer compounds and polymer light emitting devices made by using the same | Sumitomo Chemical Company, Limited (JP) | 2011-05-25 | — | — | EP | disclosed |