Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24564907 | 0.87 | MAPT (0.50) | MAPTALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL203439 | 0.87 | MAPT (0.50) | MAPTALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL29654967 | 0.87 | MAPT (0.50) | MAPTALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL12658735 | 0.82 | PDE2A (0.49) | MAPTALDH1A1KDM4ELMNAPIM1 | |
| SCHEMBL13070979 | 0.82 | PDE2A (0.49) | MAPTALDH1A1KDM4ELMNAPIM1 | |
| SCHEMBL12675062 | 0.79 | PIM1 (0.46) | MAPTKDM4ESMN1; SMN2HSD17B10AHR | |
| SCHEMBL30693959 | 0.78 | PIM1 (0.48) | MAPTALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL3771900 | 0.78 | PIM1 (0.48) | MAPTALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL259160 | 0.77 | AHR (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL12325043 | 0.77 | AHR (0.59) | MAPTALDH1A1KDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225610-A1 | METHOD FOR MANUFACTURING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2017-10-04 | — | — | EP | disclosed |