Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945065 | 0.88 | PTPN2 (0.44) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL14722991 | 0.88 | PTPN2 (0.44) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL12658772 | 0.88 | PTPN2 (0.44) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL25666955 | 0.85 | PNLIP (0.53) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL25667484 | 0.85 | PNLIP (0.53) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL25434656 | 0.80 | PNLIP (0.46) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL25439738 | 0.80 | PNLIP (0.46) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL25436685 | 0.80 | PNLIP (0.46) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL31592688 | 0.80 | PNLIP (0.46) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 | |
| SCHEMBL30585227 | 0.80 | PNLIP (0.46) | PNLIPPTPN2PTPN1RPS6KA5MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143703-B1 | Method for the preparation of (+)-totarol | COGNIS IP MAN GMBH (DE) | 2011-05-18 | — | — | EP | disclosed |