SCHEMBL1265972

SCHEMBL1265972

CC(C)=CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.89

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAA50 Q9GZZ1 2/20 0.89
CHAT P28329 2/20 0.83
EP300 Q09472 4/20 0.82
KAT5 Q92993 2/20 0.82
AURKA O14965 2/20 0.82
KAT2B Q92831 1/20 0.82
CREBBP Q92793 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17593355 1.00 NAA50 (0.89) NAA50CHATEP300KAT5AURKA
SCHEMBL20211012 1.00 NAA50 (0.89) NAA50CHATEP300KAT5AURKA
SCHEMBL16018847 1.00 NAA50 (0.89) NAA50CHATEP300KAT5AURKA
SCHEMBL29425225 1.00 NAA50 (0.89) NAA50CHATEP300KAT5AURKA
Water SCHEMBL15758537 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
SCHEMBL25286759 0.98 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
SCHEMBL29849789 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL29238963 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL30221151 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL30009559 0.96 NAA50 (0.86) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497635-B2 Means and methods for producing isobutene from acetyl-CoA GLOBAL BIOENERGIES (FR) 2025-12-16 US claimed
US-12460234-B2 Synthesis of isoprenoids and derivatives WILLIAM MARSH RICE UNIVERSITY (US) 2025-11-04 US claimed
US-20250333769-A1 ACYL-COA HYDROLASE VARIANTS GLOBAL BIOENERGIES (FR) 2025-10-30 US claimed
US-20250327097-A1 ORGANISMS PRODUCING LESS CROTONIC ACID GLOBAL BIOENERGIES (FR) 2025-10-23 US claimed
CN-113614240-B Improved means and methods for producing isobutene from acetyl-CoA 环球生物能源公司 2024-12-13 CN claimed
US-20240366543-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA HEMOSHEAR THERAPEUTICS INC (US) 2024-11-07 US claimed
EP-4448779-A1 ACYL-COA HYDROLASE VARIANTS Global Bioenergies (FR) 2024-10-23 EP claimed
EP-4399284-A1 ORGANISMS PRODUCING LESS CROTONIC ACID Global Bioenergies (FR) 2024-07-17 EP claimed
EP-4319746-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA Hemoshear Therapeutics, Inc. (US) 2024-02-14 EP claimed
WO-2023110750-A1 ACYL-COA HYDROLASE VARIANTS GLOBAL BIOENERGIES (FR) 2023-06-22 WO claimed
WO-2014085612-A1 METHODS FOR BIOSYNTHESIS OF ISOBUTENE INVISTA North America S.á r.l. (US) 2014-06-05 WO claimed
WO-2013053824-A1 NEW BIOSYNTHESIS PATHWAY FOR PRENOL IN A RECOMBINANT MICROORGANISM METABOLIC EXPLORER (FR) 2013-04-18 WO claimed
US-20110201067-A1 METHOD FOR PREPARING POLYLACTATE AND COPOLYMER THEREOF USING A MUTANT MICROORGANISM WITH ENHANCED POLYLACTATE, AND THE COPOLYMER PRODUCING CAPABILITY THEREOF LG CHEM, LTD 2011-08-18 US claimed
WO-2011051813-A1 COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS PAUL HARBHAJAN S (US) 2011-05-05 WO claimed
US-20110098229-A1 COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS BIOMED RESEARCH & TECHNOLOGIES, INC. 2011-04-28 US claimed
EP-2314638-A2 METHOD FOR PREPARING POLYLACTATE AND COPOLYMER THEREOF USING A MUTANT MICROORGANISM WITH ENHANCED POLYLACTATE, AND THE COPOLYMER PRODUCING CAPABILITY THEREOF LG Chem, Ltd. (KR) 2011-04-27 EP claimed
WO-2009064910-A2 DIMETHYLOCTANE AS AN ADVANCED BIOFUEL SYNTHETIC GENOMICS, INC. (US) 2009-05-22 WO claimed
EP-1098630-A2 COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION Biomed Research and Technologies, Inc. (US) 2001-05-16 EP claimed
US-6149924-A FOR TOPICAL APPLICATION BIOMED RESEARCH & TECHNOLOGIES, INC. (US) 2000-11-21 US claimed
WO-2000004870-A2 COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION BIOMED RESEARCH AND TECHNOLOGIES, INC. (US) 2000-02-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366543-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA MMAB, OTC, ME2 NAA50 3556/4885CHAT 1146/4885EP300 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.