Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881668 | 0.78 | CACNA2D1 (0.33) | CACNA2D1 | |
| SCHEMBL9734543 | 0.73 | ALPL (0.32) | CACNA2D1 | |
| SCHEMBL20368859 | 0.70 | ALPL (0.30) | — | |
| SCHEMBL14700163 | 0.69 | — | — | |
| SCHEMBL8406299 | 0.67 | — | — | |
| SCHEMBL27898978 | 0.65 | — | — | |
| SCHEMBL26381425 | 0.63 | PLD2 (0.30) | — | |
| SCHEMBL27881670 | 0.62 | — | — | |
| SCHEMBL7905340 | 0.61 | TSHR (0.44) | — | |
| SCHEMBL27881682 | 0.61 | PIK3CD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125748-B1 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2011-05-25 | — | — | EP | disclosed |