Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866527 | 0.85 | MEN1 (0.65) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL1861272 | 0.82 | CYP1A2 (0.58) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL12660795 | 0.81 | CYP1A2 (0.61) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL1864484 | 0.81 | CYP1A2 (0.61) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL3228832 | 0.80 | DCTPP1 (0.64) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL1866781 | 0.79 | ALDH1A1 (0.58) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL1862003 | 0.78 | ALDH1A1 (0.62) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL12929345 | 0.76 | ALDH1A1 (0.78) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL12929685 | 0.76 | MAPT (0.55) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL12929724 | 0.75 | ALDH1A1 (0.63) | CYP1A2POLBCYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053705-A1 | PYRIMIDINE COMPOUNDS AS DELTA OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-05 | — | — | WO | disclosed |