SCHEMBL12667474

SCHEMBL12667474

CC(C)(C)OC(=O)NCCC[C@H](N)CO

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.64
GAA P10253 1/20 0.64
KMT2A Q03164 1/20 0.64
TDP1 Q9NUW8 1/20 0.58
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
CA1 P00915 12/20 0.46
CA2 P00918 12/20 0.46
CA12 O43570 6/20 0.46
CA9 Q16790 6/20 0.46
STK17B O94768 1/20 0.41
STK17A Q9UEE5 1/20 0.41
EPHX1 P07099 1/20 0.39
HTT P42858 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22574596 1.00 MEN1 (0.64) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4107078 0.95 TDP1 (0.61) MEN1GAAKMT2ATDP1MAOA
SCHEMBL30915267 0.95 TDP1 (0.61) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4107080 0.95 TDP1 (0.61) MEN1GAAKMT2ATDP1MAOA
SCHEMBL19007632 0.90 MEN1 (0.54) MEN1GAAKMT2ATDP1MAOA
SCHEMBL12954842 0.90 MEN1 (0.54) MEN1GAAKMT2ATDP1MAOA
SCHEMBL12668248 0.89 MEN1 (0.62) MEN1GAAKMT2ATDP1MAOA
SCHEMBL6665327 0.87 MEN1 (0.64) MEN1GAAKMT2ATDP1MAOA
SCHEMBL21190311 0.86 MEN1 (0.62) MEN1GAAKMT2ATDP1MAOA
Hydrochloric Acid SCHEMBL6122869 0.86 MEN1 (0.62) MEN1GAAKMT2ATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511740-B Amide substituted imidazo [4,5-C ] quinoline compounds with branched linking groups for use as immune response modifiers 3M创新有限公司 2023-05-16 CN disclosed
US-11306083-B2 Amide substituted imidazo[4,5-C]quinoline compounds with a branched chain linking group for use as an immune response modifier 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-19 US disclosed
EP-3728255-B1 AMIDE SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH A BRANCHED CHAIN LINKING GROUP FOR USE AS AN IMMUNE RESPONSE MODIFIER 3M INNOVATIVE PROPERTIES CO (US) 2022-01-26 EP disclosed
US-20210101898-A1 AMIDE SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH A BRANCHED CHAIN LINKING GROUP FOR USE AS AN IMMUNE RESPONSE MODIFIER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-04-08 US disclosed
EP-3728255-A1 AMIDE SUBSTITUED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH A BRANCHED CHAIN LINKING GROUP FOR USE AS AN IMMUNE RESPONSE MODIFIER 3M Innovative Properties Company (US) 2020-10-28 EP disclosed
EP-1697400-B1 BIPHENYL-SUBSTITUTED ANTIBACTERIAL MACROCYCLES AICURIS GMBH & CO KG (DE) 2011-05-25 EP disclosed
US-7655643-B2 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2010-02-02 US disclosed
US-20070099885-A1 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099885-A1 Antibacterial macrocycles with substituted biphenyl NOD2, AHR, BCL2 MEN1 1957/4885GAA 810/4885KMT2A 3328/4885
US-20210101898-A1 AMIDE SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH A BRANCHED CHAIN LINKING GROUP FOR USE AS AN IMMUNE RESPONSE MODIFIER IFNG, IFNAR1, IL2 MEN1 2411/4885GAA 2198/4885KMT2A 2685/4885
US-11306083-B2 Amide substituted imidazo[4,5-C]quinoline compounds with a branched chain linking group for use as an immune response modifier IFNG, IFNAR1, IL2 MEN1 2411/4885GAA 2198/4885KMT2A 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.