Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871934 | 0.85 | BACE1 (0.46) | SMN1; SMN2HSD17B10BACE1NCF1NPSR1 | |
| SCHEMBL7033224 | 0.82 | CD38 (0.50) | CD38SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1871110 | 0.79 | FABP4 (0.49) | SMN1; SMN2MEN1KMT2APOLBKDM4E | |
| SCHEMBL6617291 | 0.74 | NQO2 (0.67) | CD38SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL3058825 | 0.74 | CYP2C19 (0.64) | CD38SMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL20680443 | 0.73 | CD38 (0.66) | CD38MEN1KMT2ACYP2C19MAPT | |
| SCHEMBL13779517 | 0.73 | HTT (0.51) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL6128195 | 0.71 | MEN1 (0.72) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL19539195 | 0.71 | HTT (0.59) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9363750 | 0.71 | MEN1 (0.61) | CD38SMN1; SMN2MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |