Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669337 | 0.85 | CD38 (0.50) | BACE1SMN1; SMN2HSD17B10NPSR1NCF1 | |
| SCHEMBL1871110 | 0.81 | FABP4 (0.49) | BACE1SMN1; SMN2APP | |
| SCHEMBL1871546 | 0.76 | MAPT (0.49) | SMN1; SMN2NPSR1 | |
| SCHEMBL17807836 | 0.76 | BACE1 (0.58) | BACE1SMN1; SMN2APPHSD17B10NPSR1 | |
| SCHEMBL7022867 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2APPNPSR1DHFR | |
| SCHEMBL3853354 | 0.70 | BACE1 (0.51) | BACE1APPHSD17B10 | |
| SCHEMBL7033224 | 0.70 | CD38 (0.50) | BACE1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL1519151 | 0.69 | SMN1; SMN2 (0.47) | BACE1SMN1; SMN2APPHSD17B10 | |
| SCHEMBL3235742 | 0.69 | SMN1; SMN2 (0.47) | BACE1SMN1; SMN2APPHSD17B10 | |
| SCHEMBL12164325 | 0.69 | MAPT (0.57) | SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |