Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | YARS1 | P54577 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669642 | 0.93 | BLM (0.47) | BLMTSHRNPSR1TDP1LMNA | |
| SCHEMBL10456166 | 0.83 | BLM (0.59) | BLMTSHRNPSR1TDP1LMNA | |
| SCHEMBL180939 | 0.78 | SRC (0.54) | BLMTDP1LMNAPTGS1ADRA1A | |
| SCHEMBL27577340 | 0.76 | SRC (0.52) | BLMTDP1LMNAPTGS1ADRA1A | |
| SCHEMBL27473645 | 0.76 | SRC (0.52) | BLMTDP1LMNAPTGS1ADRA1A | |
| SCHEMBL13749426 | 0.76 | ESR1 (0.42) | BLMTSHRNPSR1LMNAYARS1 | |
| SCHEMBL13749036 | 0.74 | ESR1 (0.40) | BLMTSHRNPSR1LMNAYARS1 | |
| SCHEMBL22959423 | 0.73 | BLM (0.58) | BLMTSHRTDP1LMNANR1I2 | |
| SCHEMBL2942876 | 0.73 | CNR1 (0.54) | TDP1LMNASRCALDH1A1KMT2A | |
| SCHEMBL352555 | 0.72 | LMNA (0.65) | BLMTSHRNPSR1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112260-A1 | COMPOSITION COMPRISING A BLEND OF RESINS | DSM IP ASSETS B.V. (NL) | 2011-05-12 | — | — | US | disclosed |
| US-20110112260-A1 | COMPOSITION COMPRISING A BLEND OF RESINS | DSM IP ASSETS B.V. (NL) | 2011-05-12 | — | — | US | disclosed |
| US-20110086988-A1 | COMPOSITION COMPRISING POLYOLS | EVONIK DEGUSSA GMBH (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20110086988-A1 | COMPOSITION COMPRISING POLYOLS | EVONIK DEGUSSA GMBH (DE) | 2011-04-14 | — | — | US | disclosed |